Anatomy-Physiotherapy-logo

  • Italiano (Italia)
  • Français (France)
  • Portuguese (PT)
  • Deutsch (Deutschland)
  • Spanish (ES)
  • English (UK)
New english website, click here ->

           

  • Articles
    Evidence based articles
    • Musculoskeletal
      • Upper extremity
      • Lower extremity
      • Spine
    • Other
      • Nervous
      • Circulatory
      • Nutrition
      • Aging
      • Pain
      • Various
  • Art & Design
    Anatomy related art
  • Videos
    Webinars & more
  • Create account
    Personal pages & favourites
  • Login
    Login to A&P
Anatomy-Physiotherapy-logo
30 Sep2013

30 September 2013.

Written by Miranda Asher
Posted in Hand

Written by Miranda Asher30-09-2013 18:16:38. Posted in Hand

Hand transplant.
Hand transplant. (Image by: a-s-r-t.com)

Outcomes with respect to disabilities of the upper limb after hand allograft transplantation: a systematic review.

Hand allograft transplantation (HAT) refers to the grafting of a donor hand onto another person's forearm including; bone, artery, tendon, nerve and vein. More than 50 of these operations have been performed worldwide. Alongside the need for long term use of immunosuppresive (IS) drugs, the adoption of HAT has been stunted by limited evidence of improvement in upper limb function. 

This paper retrospectively reviewed 28 HATs, looking at outcome measures including; DASH (Disabilities of the arm, shoulder and hand) and HTSS (hand transplant score system.) In 57% of the reviewed cases the intrinsic muscle function was observed post transplant, indicating good quality neural repair within a short time frame. 

The review confirmed a significant improvement in upper limb functionality, with possible implication that bilateral allografts gain more functionality than unilateral (although inconclusive.) Significantly there were 52 complications noted within this group of 28 recipients, due to use of IS. It was also noted that the time between amputation and transplant did not show influence on function recovery, with one case stating a 28 year gap. 

The authors indicate that the lack of a control group limits the study, concluding that HAT should be offered only to selected candidates as, although there is functional gain, the associated risk of complication due to chronic IS therapy is high. > From: Landin et al., Transpl Int, 25 (2012) 424-432. All rights reserved to European Society for Organ Transplantation.

The free full text article can be read here.

See the story, and operation, of a young woman who receives a hand allograft in the YouTube clip below.

Hand transplant.
Hand transplant.
(Image by: www.washingtonpost.com)

Tags: hand allograft transplantation, hand, allograft, disabilities, upper extremity, upper limb, transplantation

Please log in or create an account to place comments. It's free and takes only a minute.

About the Author
Miranda Asher

Latest articles from this auhtor

  • Review of hybrid exoskeletons to restore gait following spinal cord injury.
  • Review of hybrid exoskeletons to restore gait following spinal cord injury.
  • Effect of peroneal electrical stimulation versus an ankle-foot orthosis on obstacle avoidance ability in people with stroke-related foot drop.
  • The effects of ankle foot orthoses on energy recovery and work during gait in children with cerebral palsy.
  • Body integrity identity disorder.
 

 

Login

  • Forgot your password?
  • Forgot your username?
  • Create an account
AP banner Sono 1

Related

  • The incredible human hand
  • Current concepts: mallet finger
  • Scaphoid fractures - diagnostic tests and clinical reasoning
  • Real time visualization of joint cavitation
  • Provocative tests for the elbow, wrist and hand

Sub Menu

  • Musculoskeletal
    • Upper extremity
      • Shoulder
      • Elbow
      • Wrist
      • Hand
    • Lower extremity
      • Hip
      • Knee
      • Ankle
      • Foot
    • Spine
      • Pelvis
      • Lumbar
      • Thoracic
      • Rib cage
      • Cervical
  • Other
    • Nervous
    • Circulatory
    • Nutrition
    • Aging
    • Pain
    • Various

Newsletter

Subscribe to our weekly newsletter to receive all articles of the week in your mailbox.

 

Partners

enraf nonius

apa

fontys

vpt

kiné care

ICMSU

  • Home
  • About
  • Team
  • Advertise
  • Contact
  • Terms of Service
  • Privacy Policy
  • Jobs
  • Newsletter archive
AP-SMALL-WHITECopyright 2010 - 2023 Anatomy & Physiotherapy. All Rights Reserved.

Privacy Policy

AdBlock detected

We want to keep offering top-notch content for free. In order to keep up with the additional costs that we incurr with scaling our website, we need your help! Please turn off your adblocker or consider donating a small amount.

http://www.anatomy-physiotherapy.com/donate

Close
You can also just close this popup. It shows only once.
isApp.it
  • Articles
    Evidence based articles
    • Musculoskeletal
      • Upper extremity
        • Shoulder
        • Elbow
        • Wrist
        • Hand
      • Lower extremity
        • Hip
        • Knee
        • Ankle
        • Foot
      • Spine
        • Pelvis
        • Lumbar
        • Thoracic
        • Rib cage
        • Cervical
    • Other
      • Nervous
      • Circulatory
      • Nutrition
      • Aging
      • Pain
      • Various
  • Art & Design
    Anatomy related art
  • Videos
    Webinars & more
  • Create account
    Personal pages & favourites
  • Login
    Login to A&P
You are now being logged in using your Facebook credentials